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We can test up to six samples to be measured at the same time using the TethaPlate sample holders. Ideal for studies of embedded ion channel proteins, including screening experiments for potential pharmaceuticals.

Each experiment is conducted on millions of 'parallel' ion channels giving a large total ion current, negating the need for the high gain amplifiers and complicated electronics typical of single channel recording techniques, such as patch clamping. Moreover, the use of proteins grown by bacterial culture, and purified by modern proteomic methods, ensures that the response is from a single type of ion channel, unlike the results from whole cell, or oocyte, voltage clamping, or Ussing chamber experiments.

Each TethaPod (May 2015 or later) is supplied with tethaQuick software to display, store and graph membrane resistance, conductance and capacitance values versus time. Data can be easily exported to Excel or similar software for dose response or other calculations.

Features of TethaPod™  SDx - R1

• USB powered
• Plug and play software
• Graphs and tabulates membrane conductance
• Measures from six sample chambers in tethaPlate
• Compact. Use with netbook for tiny footprint!

Applications

• Biophysics: examine phospholipid mixtures for the ability to form coherent bilayer membranes. 
• Proteomics: check protein fractions to determine membrane compatibility and ion channel activity.
• Pharmacology: Screening assays and dose/response experiments on ion channel toxins, blockers, and activators.
• Electrophysiology: ion channel behaviour.

Compatibility

• The TethaPod connects via USB (as a virtual serial, or COM, port device) to Windows XP, Windows Vista, or Windows 7 computers.

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To contact eDAQ about eDAQ | TethaPod | SDx-R1 use Get a quote.